Yaone of Saiyuki is an apothecary, alchemist, skilled fighter, and watches after Lirin.
Yaone is deeply devoted to Kougaiji, who saved her from being sacrificed to the Centipede Demon, and has rashly taken on dangerous missions to prove her loyalty to him. As a trained chemist, she also serves as the group's healer. She seems to be friendly enemies with Cho Hakkai; she always addresses him with great respect, and on occasions they work together.
In the Japanese version, she is voiced by Yuko Minaguchi. In the English version, she is voiced by Shelley Calene-Black in the original series and by Mela Lee in Reload and Reload: Gunlock.