Sherry Birkin is the daughter of William and Annette Birkin. She first appears in Resident Evil 2, running away and hiding in Raccoon City during the outbreak.
She manages to find Leon and Claire, who protect her while trying to escape the city. Sherry is a playable character in some parts of the game but she is completely unarmed and can only avoid the monsters. Her father has been transformed into a monstrous creature by the G-virus and infects his daughter, but Claire gives Sherry an anti-virus, which prevents her from mutating. Sherry assists Leon and Claire in boarding a secret underground train, and successfully escapes Raccoon City before it is destroyed. Sherry also appears in Resident Evil: The Darkside Chronicles in chapters that recapitulate the events of Resident Evil 2. She returns as an adult in Resident Evil 6 as a government agent escorting Jake Muller and seems to have acquired great healing abilities from the remnants of the G-virus in her body. During the course of the game, she helps Jake deal with the fact that Albert Wesker is his father. She also learns from Leon S. Kennedy that her superior, Derek C. Simmons, is the man responsible for the U.S. President's death. She and Jake subsequently ally with Leon, Chris Redfield and their partners in thwarting Carla Radames' plans. Sherry and Jake appear to have become closer during and after their life-threatening journey, developing a strong sense of trust over their similar life experiences. There's also hinted to be some sort of romance between the two.
Sherry Birkin is voiced by Lisa Yamanaka (RE2), Laura Bailey (The Darkside Chronicles), Eden Riegel (Operation Raccoon City, RE6), Hisako Kanemoto (Operation Raccoon City (Japanese)), Maaya Sakamoto (RE6 (Japanese)).